Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)


Medical immunology

Shibuya Project

The immune system is crucial to human survival. In the absence of the immunity, even minor infections prove fatal. The immune system is also involved in the pathogenesis of autoimmune diseases, allergy, cancer, and rejection of organ transplantation. It is therefore important to understand the immune responses. Our laboratory focuses on the study of molecular and cellular bases how the immune system protect us from these intractable diseases.

Research Project

Medical Immunology

Akira Shibuya, M.D., Ph.D. (Professor, TARA Center)

We identified several novel immunoreceptors, including DNAM-1 (CD226), MAIR (CD300), Fcα/µR (CD351) and Allergin-1, which are involved in the development of allergy, cancer, inflammation or autoimmune diseases. Our goal is to clarify the function of these molecules in immune responses and to develop new therapies for the intractable diseases.


Life Science Center for Survival Dynamics
Tsukuba Advanced Research Alliance (TARA)

1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577 Japan
TEL: +81-29-853-6082
FAX: +81-29-853-6074

University of Tsukuba

●Center Director